发明名称 |
Stabilized vitamin D preparation. |
摘要 |
The present invention provides a pharmaceutical composition of a heat-labile vitamin D active compound dispersed in a basic polymer; a pharmaceutical composition, which comprises an excipient readily soluble in an organic solvent, a heat-labile vitamin D2 active compound and a basic substance; or a pharmaceutical composition, which comprises homogeneous dispersion of a finely pulverized heat-labile vitamin D active compound in a basic substance and an excipient readily soluble in water. In the composition of this invention, thermal isomerization, decomposition and discoloration is remarkably reduced, keeping excellent stability.
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申请公布号 |
EP0508756(A1) |
申请公布日期 |
1992.10.14 |
申请号 |
EP19920303129 |
申请日期 |
1992.04.08 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
ITOH, HIROKI;TABATA, TETSURO;KIKUTA, JUN-ICHI |
分类号 |
A61K9/14;A61K9/16;A61K9/20;A61K9/48;A61K31/59;A61K47/02;A61K47/32;A61K47/38 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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