| 摘要 |
PURPOSE:To produce an alpha,beta-unsaturated ketone useful as an intermediate for pharmaceuticals, agricultural chemicals, perfumes, etc., in an industrialy advantageous manner in high yield at a low cost under mild and neutral condition. CONSTITUTION:The objective compound of formula II can be produced at a low cost by reacting a compound of formula I (R<1> and R<2> are H, alkyl or aryl; R<1> and R<2> may together form an alkylene bond; R<3> is alkyl or aryl; R<4> is alkyl) in the presence of 0.001-0.2 equivalent (preferably 0.01-0.1 equivalent) (based on the compound of formula I) of a compound of formula MAuX4 (M is alkali metal; X is halogen) or formula AuX3 in 2-100 equivalent (preferably 10-50 equivalent) (based on the compound of formula I) of a hydrated solvent at 0-100 deg.C (preferably 30-80 deg.C). The solvent is preferably an alcohol such as methanol, ethanol, 2-propanol, 1-butanol and t-butanol and the water-content of the solvent is preferably 1-20%. |
