| 摘要 |
2108255 9218485 PCTABS00016 Compounds of formula (I), in which R1 is A-N(O)R'R" and R2, R3 and R4 are each separately selected from hydrogen, X and NH-A-N(O)R'R" wherein X is hydroxy, halogeno, amino, C1-4 alkoxy or C2-8 alkanoyloxy, A is a C2-4 alkylene group with a chain length between N or NH and N(O)R'R" of at least 2 carbon atoms and R' and R" are each separately selected from C1-4 alkyl groups and C2-4 hydroxyalkyl and C3-4 dihydroxyalkyl groups in which the carbon atom attached to the nitrogen atom does not carry a hydroxy group and no carbon atom is substituted by two hydroxy groups, or R' and R" together are a C2-6 alkylene group which with the nitrogen atom to which R' and R" are attached forms a heterocyclic group having 3 to 7 atoms in the ring, and physiologically acceptable salts thereof are of value in the treatment of cancer.
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