| 摘要 |
The invention relates to a compound of the formula: <IMAGE> wherein R1 is aryl which may have suitable substituents(s), X is -O- or <IMAGE> in which R3 is hydrogen or lower alkyl, A is a bond or lower alkylene which may have lower alkyl group(s), and R2 is hydrogen; heterocyclic(lower)alkenoyl which may have carboxy or protected carboxy; heterocycliccarbonyl which may have N,N-di(lower)alkylamino(lower)alkyl, hydroxyimino(lower)alkyl, aryliminio(lower)alkyl, acyl or hydroxy(lower)alkylheterocyclic(lower)alkyl; aroyl which may have 1 to 3 substituent(s) selected from the group consisting of halogen, amino and mono(or di or tri)halo(lower)alkyl; arylcarbamoyl which may have halogen or lower alkoxy; arylamino(lower)alkanoyl; or ar(lower)alkanoyl which may have amino or protected amino, or a pharmaceutically acceptable salt thereof, useful as a cholecystokinin antagonist.
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