发明名称 |
Phenylsulfonyl nitromethanes as aldose reductase inhibitors |
摘要 |
The invention concerns novel pharmaceutical compositions for use in the treatment of certain complications of diabetes and galactosemia and which contain a nitromethane derivative (or its non-toxic salt) as active ingredient. The nitromethane derivatives are inhibitors of the enzyme aldose reductase. Many of the inhibitors are novel and are provided, together with processes for their manufacture and use, as further features of the invention.
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申请公布号 |
US5153227(A) |
申请公布日期 |
1992.10.06 |
申请号 |
US19890306676 |
申请日期 |
1989.02.06 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES PLC |
发明人 |
BROWN, STEVEN P.;COOPER, ANTHONY L.;LONGRIDGE, JETHRO L.;MORRIS, JEFFREY J.;PRESTON, JOHN |
分类号 |
C12N9/99;A61K31/10;A61K31/135;A61K31/165;A61K31/19;A61K31/275;A61K31/335;A61K31/357;A61K31/36;A61P3/08;A61P3/10;A61P43/00;C07C67/00;C07C313/00;C07C317/14;C07C317/22;C07C317/24;C07C317/32;C07C317/36;C07C317/44;C07C323/09;C07C323/18;C07C323/22;C07C323/31;C07C323/62;C07D317/22;C07D317/60;C07D317/62 |
主分类号 |
C12N9/99 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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