Method of treating pulmonary hypertension with benzidine prostaglandins

摘要

The present invention is concerned with methods for the prophylaxis, treatment and diagnosis of pulmonary hypertension which comprise the administrative of an effective amount of a compound of formula (I) <IMAGE> (I) wherein a is an integer of from 1 to 3; X and Y, which may be the same or different, are selected from -O- and -CH2-; R is -(CH2)5R1 wherein R1 is hydrogen or methyl, or R is cyclohexyl, or R is -CH(CH3)CH2C 3BOND CCH3; and the dotted line represents an optional double bond; or of a physiologically acceptable salt or acid derivative thereof. Medicaments and diagnostic aids for use in the methods of the invention are also within the scope of the invention.