摘要 |
Pharmaceutical compositions comprising a compound of formula (I) and at least one other anthelmintically active compound, being an avermectin or a milbemycin, are useful in the treatment of helminthiasis. In formula (I): R is optionally substituted phenyl, C3-8 cycloalkyl, C5-8 cycloalkenyl, C1-8 straight or branched chain alkyl, C2-8 straight or branched alkenyl, a 5- or 6-membered heterocyclyl, or optionally substituted phenyl C1-4 alkyl; each of Y and Z, which may be the same or different, is oxygen or sulfur; and X is a bond, a methylene group (-CH2-), or oxygen. |