| 摘要 |
Disclosed herein are novel benzopyrans having pharmacologica1 activity, to a process for preparing them, to pharmaceutical compositions containing them, and to their use in the treatment of hypertension. The benzopyrans have the following formula (I) (I) wherein R1 is trifluoromethoxy or .beta.,.beta.,.beta.-trifluoroethoxy; R2 and R3 are independently selected from the group consisting of hydrogen, lower alkyl containing 1 to 5 carbon atoms, cyclo lower alkyl containing 5 to 8 carbon atoms, or R2 and R3 are joined to form ?CH2?n wherein n is 4 to 7; or R2 and R3 are joined together to form ?CH2?m?- wherein m is 3 to 6; or R2 and R3 are joined together to form or wherein R4 is selected from the group consisting of hydrogen, alkoxy containing 1 to 5 carbon atoms, amino or mono- or disubstituted alkyl amino wherein said alkyl groups contain 1 to 5 carbon atoms. |
