ON-LINE PRODUCT IDENTIFICATION IN A CHROMATOGRAPHY EFFLUENT BY SUBSTRACTION

摘要

PCT/US92/02263 Disclosed is a method and apparatus for the rapid identification of a solute of interest in an effluent stream (14). The method involves separation of the solutes in the effluent (14) and identification of a particular solute of interest by its selective subtraction from the effluent stream 914). The effluent stream (14) from a first system (12) capable of partitiuning the components of the mixture is passed through a detector (16) to produce a first output (18( which describes the temporal and/or spacial sequence of the mixture components exiting the first system (12). The effluent stream (14) is then passed through a second system (20) capable of selectively extracting a solute of interest from said effluent stream (14) and is then passed through a detector (16).