| 发明名称 |
PROCESS FOR PRODUCING POLYETHYLENE GLYCOL CONJUGATES OF PROTEINS |
| 摘要 |
The present invention relates to physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugates having at least part of the biological activity of the protein which forms the conjugate, without exhibiting the same disadvantageous immunogenic responses thereof.
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| 申请公布号 |
HUT60512(A) |
申请公布日期 |
1992.09.28 |
| 申请号 |
HU19920000955 |
申请日期 |
1992.03.23 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG.,CH |
发明人 |
HAKIMI,JOHN,US;KILIAN,PATRICIA,US;ROSEN,PERRY,US |
| 分类号 |
A61K38/00;A61K;A61K31/745;A61K38/16;A61K38/19;A61K38/20;A61K38/21;A61K39/00;A61K39/38;A61K39/385;A61K47/42;A61K47/48;A61P37/00;A61P37/02;A61P43/00;C07C267/00;C07C331/18;C07C331/20;C07D211/04;C07D213/63;C07D213/64;C07D213/643;C07D213/70;C07D213/83;C07D213/89;C07K;C07K1/00;C07K14/47;C07K14/52;C07K14/54;C07K14/545;C07K14/55;C07K14/555;C07K14/56;C07K14/765;C07K17/00;C07K17/02;C07K17/06;C07K17/08;C07K17/10;C08F116/02;C08F216/00;C08G65/02;C08G65/08;C08G65/26;C08G65/28;C08G65/32;C08G65/34;C08G65/48;C08H1/00;C08L23/36;C08L71/02;C12N9/96;(IPC1-7):C07K17/10 |
主分类号 |
A61K38/00 |
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