发明名称 PROCESS FOR PRODUCING LEUSTRODUXINE DERIVATIVES
摘要 New compounds, which we have named the "Leustroducsins" have the formula (I): <CHEM> in which R represents a 5-methylhexanoyloxy group, a 6-methyloctanoyloxy group or a 7-methyloctanoyloxy group, and salts thereof, and may be prepared by fermentation using a microorganism of the genus Streptomyces, especially a strain of the species Streptomyces platensis, such as strain SANK 60191 (FERM BP-3288). These compounds may be used for the treatment or prophylaxis of: adverse reactions resulting from cancer chemotherapy or radiotherapy; infections; cancer; cerebral dysfunction; and fungal infections.
申请公布号 HUT60521(A) 申请公布日期 1992.09.28
申请号 HU19920001005 申请日期 1992.03.25
申请人 SANKYO CO 发明人 KOHAMA TAKAFUMI;NAKAMURA TAKEMICHI;KAGASAKI TAKESHI;KANEKO ISAO;MATSUDA KEIICHI;ENOKITA RYUZO
分类号 C07D309/38;A61K31/655;A61K31/665;A61P7/00;A61P31/10;C07F9/117;C07F9/655;C12N1/14;C12P9/00;C12P17/06;C12R1/465;(IPC1-7):C12N1/14 主分类号 C07D309/38
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