| 发明名称 |
N-ACYL-ALFA-AMINOSYREDERIVATER |
| 摘要 |
<p>N-Aroyl- alpha -aminocarboxylic acid derivatives of the formula <IMAGE> in which L, R' to R''' and Q have the meaning given in the description, can be used for the treatment or prophylaxis of diseases which are caused by the binding of adhesive proteins to blood platelets, as well as by blood platelet aggregation and cell-cell adhesion. They are prepared by removing protective groups in appropriately protected compounds or by conversion of the cyano group to the amidino group in appropriate nitriles.</p> |
| 申请公布号 |
NO921169(A) |
申请公布日期 |
1992.09.28 |
| 申请号 |
NO19920001169 |
申请日期 |
1992.03.25 |
| 申请人 |
HOFFMANN LA ROCHE |
发明人 |
ALIG LEO;HADVARY PAUL;HUERZELER MARIANNE;MUELLER MARCEL;STEINER BEAT;WELLER THOMAS |
| 分类号 |
A61K31/155;A61K;A61K31/165;A61K31/195;A61K31/198;A61K31/445;A61K31/451;A61P7/02;A61P7/04;C07C227/00;C07C229/00;C07C229/10;C07C233/76;C07C237/22;C07C257/18;C07C279/18;C07D;C07D207/08;C07D207/12;C07D207/16;C07D211/22;C07D211/40;C07D211/42;C07D211/44;C07D211/46;C07D211/48;C07D211/52;C07D401/06;C07D401/12;C07D451/06;C07D453/06;(IPC1-7):C07D211/46;C07D451/02 |
主分类号 |
A61K31/155 |
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