DERIVATIVES OF SUBSTITUTED IMIDAZOL-2-ONE AND PROCESS FOR THEIR PREPARATION

摘要

Derivatives of 1-phenyl-3-azabicycloalkylimidazolidin-2- ones are provided of general formula (I) in which inter alia R3 represents a group (see formula I and II) wherein n is an integer of 1 or 2 and R8 is hydrogen, C1-C6 alkyl unsubstituted or substituted by phenyl, C2-C4 alkenyl, C2-C4 alkynyl, formyl or C2-C6 alkanoyl; and the pharma- ceutically acceptable salts thereof, which are useful in the treatment of CNS disorders, gut motility disorders, emesis and migraine, as cognition activators, anti-drug addition agents and analgesic.