A device for use in cryopreservation of blood vessels comprising a pair of stylets insertable into the ends of a dissected blood vessel segment. The stylets are mountable on a support track whereby the blood vessel can be distended and supported during cryopreservation procedures. Also disclosed is a freezing and thawing profile capable of maximizing endothelial cell survival. The use of chondroitin sulfate or similar compound is discussed as a novel cryoprotectant and DMSO is disclosed as a penetrating cyroprotectant.
申请公布号
US5149621(A)
申请公布日期
1992.09.22
申请号
US19900436364
申请日期
1990.01.23
申请人
CRYOLIFE, INC. & MEDICAL UNIV. OF SOUTH CAROLINA
发明人
MCNALLY, ROBERT T.;MCCAA, CAMERON;BROCKBANK, KELVIN G. M.;HEACOX, ALBERT E.;BANK, HARVEY L.