| 摘要 |
PURPOSE: To provide a process for the purification and concentration of biologically active material and its solvent membrane, in particular a process for the purification and/or concentration by the means comprising applying at least one compound selected from biologically active substances having a molecular weight below 1,500, present in an initial admixture with organic solvent media and their mixtures with water, firstly under superatmospheric pressure to the feed surface of a solvent stable. CONSTITUTION: Biologically active substances having a molecular weight below 1,500, present in an initial admixture with organic solvent media and their mixtures with water, are purified and/or concentrated by a method comprising applying the initial admixture under superatmospheric pressure to the feed surface of a solvent stable membrane which is additionally characterized by the fact that it simultaneously has properties (1) rejecting at least part of such substance in the initial admixture, and (2) allowing the permeation of at least part of the medium, the balance of properties (1) and (2) being such that there accumulates at the membrane feed surface the biologically active substances in admixture with at least part of the medium, in a concentration which is higher than that in the initial admixture. |
