COMPOSITION PHARMACEUTIQUE IMPLANTABLE, BIORESORBABLE A BASE DE POLY(ACIDE LACTIQUE), DESTINEE A METTRE EN ÓOEUVRE UNE ANTIBIOTHERAPIE INTERNE LOCALE.

摘要

Implantable poly(lactic acid)-based pharmaceutical composition which comprises at least one water-soluble antibiotic in particle form with controlled dimensions, less than 100 mu m uniformly dispersed in an amorphous poly(lactic acid) matrix, said composition being in ground powder or thin film form. Application especially in initiating local internal antibiotic therapy by the gradual release of the antibiotic substance.