发明名称 RECEPTOR MEMBRANES AND IONOPHORE GATING
摘要 The present invention provides a device adapted for implantation in a mammalian body which is coated with a membrane comprising a closely packed array of self-assembling amphiphilic molecules and receptor molecules, the receptor molecules being such that the attachment of specific cells to the membrane is enhanced or avoided. For example the receptor molecules may be directed against fibronectin, vitronectin, endothelial cells, or epithelial cells. It is also preferred that the membrane coating includes a plurality of ion channels such as gramicidin. <IMAGE>
申请公布号 EP0455705(A4) 申请公布日期 1992.09.16
申请号 EP19900902588 申请日期 1990.01.29
申请人 AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE LTD. 发明人 CORNELL, BRUCE, ANDREW;BRAACH-MAKSVYTIS, VIJOLETA, LUCIJA, BRONISLAVA;PACE, RONALD, JOHN;KING, LIONEL, GEORGE;RAGUSE, BURKHARD;BAXTER, CLAIRE, ROSEMARY;HALL, RUTH, MILNE;MORRIS, CAROL, ANN;OSMAN, PETER, DAMIEN, JOHN
分类号 A61K39/00;A61K39/395;A61L27/22;A61L27/28;A61L27/54;A61L33/00;B01D69/02;B01D69/12;B01D69/14;C07K14/42;C07K16/00;C07K17/08;C07K19/00;G01N27/327;G01N27/333;G01N33/543;G01N33/566;G01N33/577;(IPC1-7):C07K17/08;A61M31/00;G01N33/544 主分类号 A61K39/00
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