发明名称 |
METHOD FOR THE PREPARATION OF 3- METHOXY- 4- /1- METHYL- 5-/ 2- METHYL- 4, 4, 4- TRIFLUOROBUTYLCARBAMOIL/INDOL- 3- IL- METHYL/N- /2- METHYLPHENYLSULFONYL/BENZAMIDE |
摘要 |
This method is used in medicine for deriving medication, which antagonizes the pharmacological action of leukotrienes. By this method, a new compound is derived, which has useful pharmacological properties. The method in fact acylates 2-methyl-4,4,4-trifluorbutylamine with 4-/5-carboxi-1-methylindol-3-il-methyl/-3-metoxi-N-/2-methylphenylsulphonyl/benzamide in the presence of a dehydrating substance or with a reacting derivative compound.
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申请公布号 |
BG50606(A3) |
申请公布日期 |
1992.09.15 |
申请号 |
BG19900095502 |
申请日期 |
1990.12.10 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES PLC |
发明人 |
JACOBS, ROBERT T. |
分类号 |
A61K31/40;A61K31/403;A61K31/404;A61K31/405;A61P9/00;A61P29/00;A61P37/08;A61P43/00;C07C211/03;C07C211/06;C07C211/07;C07C211/15;C07C233/11;C07D209/12;C07D209/14;C07D209/18;C07D209/24;(IPC1-7):C07D209/24 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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