发明名称 PLATIUM COMPOUNDS SUITABLE FOR USE AS PHARMACEUTICALS
摘要 Compound of the formula: wherein each of R1 and R2 is independently selected from the group consisting of halogen, hydroxy, or mono carboxylic acid or R1 and R2 together is a multifunctional carboxylic acid residue which forms a ring with the platinum atom through two oxygens of said multifunctional carboxylic acid; and R3 is a deoxy mono or disaccharide or a derivative thereof; and R4 is selected from the group consisting of hydrogen, C1-4-alkyl, phenyl, benzyl, substituted phenyl or substituted benzyl, wherein substituents are selected from the group consisting of halogen, nitro, C1-2-alkoxy, carboxy, carbonyl ester or phenyl or a pharmaceutically acceptable salt thereof are disclosed. Compositions containing these compounds and methods using these compounds are also discussed.
申请公布号 CA1307523(C) 申请公布日期 1992.09.15
申请号 CA19880572281 申请日期 1988.07.18
申请人 TALEBIAN, ABDOLHOSSEN 发明人 TALEBIAN, ABDOLHOSSEN;GREEN, DIANNA C.;HAMMER, CHARLES F.;SCHEIN, PHILIP S.
分类号 A61K31/28;A61K31/282;A61K31/70;A61K31/7135;A61K33/24;A61P35/00;C07F15/00;C07F17/02;C07H11/00;C07H23/00 主分类号 A61K31/28
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