发明名称 |
PROCESS FOR PRODUCING L--g(b)-HALOALANINE. |
摘要 |
<p>A process for producing L- beta -chloroalanine or L- beta -bromoalanine, which comprises bringing 3-chloro-2-ketobutyric acid or 3-bromo-2-ketobutyric acid as a substrate into contact with an active substance capable of asymmetrically reducing and aminating 2-ketobutyric acid in the presence of the reduced form nicotinamide-adenine-dinucleotide (NADH) and an ammonia source. Examples of the active substance include those having alanine dehydrogenase, leucine dehydrogenase and phenylalanine dehydrogenase activities. If necessary, the above process may incorporate an NADH regenerating system.</p> |
申请公布号 |
EP0502195(A1) |
申请公布日期 |
1992.09.09 |
申请号 |
EP19910915146 |
申请日期 |
1991.08.29 |
申请人 |
NIPPON STEEL CORPORATION |
发明人 |
KATO, YASUO, NIPPON STEEL CORP., ADV. MATERIALS;FUKUMOTO, KENJI, NIPPON STEEL CORP., ADV. MATERIAL |
分类号 |
C12P13/04 |
主分类号 |
C12P13/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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