ASSAYING AGENT FOR ENDOTOXIN.

摘要

An assaying agent for endotoxin, which comprises either a limulus amoebocyte lysate and antibody against a (1 -> 3)- beta -D-glucan-sensitive factor or a limulus amoebocyte lysate which is substantially free from said factor. As this agent makes it possible to assay with high sensitivity and endotoxin originating in Gram-negative bacteria present in a biological specimen such as blood, urine or cerebrospinal fluid without being affected by (1 -> 3)- beta -D-glucan, it serves to diagnose gram-negative bacterial sepsis or other diseases which have been difficult to diagnose rapidly with good reproducibility, thus greatly contributing to clinical examination in particular.