| 发明名称 |
PROCESS FOR THE DEVELOPMENT OF BINDING MINI-PROTEINS |
| 摘要 |
2105300 9215677 PCTABS00016 Genes encoding disulfide-bonded micro-proteins and metal ion-coordinated mini-proteins are semi-randomly mutagenized and expressed in suitable cells so as to result in the simultaneous display of the different mutant proteins on the surfaces of bacterial cells, spores or phage; the resulting display library is screened for members having the ability to bind to a target of interest.
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| 申请公布号 |
CA2105300(A1) |
申请公布日期 |
1992.09.02 |
| 申请号 |
CA19922105300 |
申请日期 |
1992.02.27 |
| 申请人 |
PROTEIN ENGINEERING CORPORATION |
发明人 |
LADNER, ROBERT C.;ROBERTS, BRUCE L.;LEY, ARTHUR C.;KENT, RACHEL B. |
| 分类号 |
C07K14/005;A61K38/00;A61Q11/00;C07K1/00;C07K1/04;C07K1/107;C07K14/00;C07K14/435;C07K14/705;C07K14/81;C12N7/00;C12N7/01;C12N15/09;C12N15/10;C12N15/12;C12N15/62;C12N15/63;C12N15/66;C12N15/70;C12P21/00;C12P21/02;C12Q1/70;C40B40/02;G01N33/53;G01N33/554;G01N33/566;(IPC1-7):C12N15/10 |
主分类号 |
C07K14/005 |
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