发明名称 PROCESS FOR THE PREPARATION OF 1-(ACYLAMINOALKYL)-2-IMIDAZOLINES SUBSTITUTED IN THE 2 POSITION
摘要 PCT No. PCT/EP89/00197 Sec. 371 Date Sep. 4, 1990 Sec. 102(e) Date Sep. 4, 1990 PCT Filed Mar. 1, 1989 PCT Pub. No. WO89/08106 PCT Pub. Date Sep. 8, 1989.In a process for preparing 2-substituted 1-(acylaminoalkyl)-2-imidazolines of the general formula I <IMAGE> (I) where R is an alkylene radical and R1 is a fatty acid radical, for example a fatty acid and a dialkylenetriamine are reacted with one another in a molar ratio of (1.8 to 2.0):1 by initially introducing one starting material at a temperature T1 and metering in the second starting material as a liquid, maintaining in the reaction mixture during the addition a temperature T1 and after the addition until the start of the cyclization a temperature T2 and distilling off the resulting water or alcohol via a rectification column and, after the acylation product has been formed, cyclizing in a conventional manner, T1 being a temperature of 170 DEG C. to the boiling point of the initially introduced starting material, but not higher than 250 DEG C., and T2 being a temperature of 170 DEG to 250 DEG C.
申请公布号 US5144040(A) 申请公布日期 1992.09.01
申请号 US19900573041 申请日期 1990.09.04
申请人 CASSELLA AKTIENGESELLSCHAFT 发明人 ECKHARDT, GEORG-WOLFGANG;KEIL, KARL-HEINZ;SCHROD, MANFRED
分类号 C07D233/16 主分类号 C07D233/16
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