发明名称 AMINOKUMARAN DERIVATIVES AND PROCESS FOR PRODUCING AMINOKUMARAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS
摘要 A novel aminocoumaran derivatives of the general formula (I): <CHEM> wherein R<1> and R<2> are a hydrogen atom, an acyl group, an alkoxycarbonyl group, an aliphatic group or aromatic group; R<3>, R<4> and R<5> are an optionally acylated hydroxyl, optionally substituted amino group, alkoxy group or aliphatic group, or two of R<3>, R<4> and R<5> may be linked together to form a carbocyclic group; R<6> and R<7> are an aliphatic group and at least one of them has a methylene group at the alpha -position; R<8> and R<9> are a hydrogen atom or an aliphatic group or aromatic group, or a salt thereof is useful for medicines for preventing and treating various diseases such as arterial sclerosis, hepatopathy, cerebrovascular diseases and the like.
申请公布号 HUT60258(A) 申请公布日期 1992.08.28
申请号 HU19910003436 申请日期 1991.10.31
申请人 TAKEDA CHEMICAL IND. LTD.,JP 发明人 AONO,TETSUYA,JP;OHKAWA,SHIGENORI,JP;DOI,TAKAYUKI,JP
分类号 A61K31/34;A61K31/343;A61K31/415;A61K31/44;A61K31/443;A61K31/445;A61P3/06;A61P9/00;A61P29/00;A61P37/08;C07C233/25;C07D307/79;C07D307/80;C07D307/81;C07D307/82;C07D405/04;C07D405/06;C07D405/12;C07D417/12;C07D521/00;(IPC1-7):C07D307/79 主分类号 A61K31/34
代理机构 代理人
主权项
地址