发明名称 |
NOVEL INSULIN ANALOGS |
摘要 |
Insulin analogues have been developed which are well suited for transdermal administration by iontophoresis. The insulin analogues have a negative charge at neutral pH and a reduced tendency to association. They are prepared by altering the human insulin molecule by substituting at least two of the amino acid residues of human insulin by Glu and/or Asp at selected positions in the molecule. |
申请公布号 |
AU1190292(A) |
申请公布日期 |
1992.08.27 |
申请号 |
AU19920011902 |
申请日期 |
1992.01.22 |
申请人 |
NOVO NORDISK A/S |
发明人 |
JENS JORGEN VEILGAARD BRANGE |
分类号 |
A61K38/28;A61K38/00;A61P3/08;A61P3/10;C07K14/575;C07K14/62;C12N15/09;C12P21/02;C12R1/865 |
主分类号 |
A61K38/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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