发明名称 NEW BENZENE DERIVATIVES HAVING NGF PRODUCTION-PROMOTING¹ACTIVITY
摘要 Novel benzene derivatives are provided of the general formula (I): <CHEM> [wherein R<1> represents an amino group, a substituted amino group, a protected amino group, or a nitro group; R<2> represents an amino group, a substituted amino group, a protected amino group, a hydroxy group, a substituted hydroxy group, or a protected hydroxy group; R<3> represents an amino group, a substituted amino, a heterocyclyl group having a ring nitrogen atom as the point of binding, or a substituted heterocyclyl group having a ring nitrogen atom as the point of binding; m is 0 to 2; n is 0 to 6; with the proviso that when m is 0, then n represents an integer from 2 to 6] and salts thereof. Compounds of formula (I) except those wherein R<1> is a nitro group have activity in promoting production of nerve growth factor. Compounds of formula (I) wherein R<1> is a nitro group are intermediates for compounds of formula (I) wherein R<1> is an amino group.
申请公布号 IE920538(A1) 申请公布日期 1992.08.26
申请号 IE19920000538 申请日期 1992.02.20
申请人 SANKYO COMPANY LIMITED 发明人 NARUTO, SHUNJI;SUGANO, YUICHI;MATSUDA, KEIICHI;SUGIMOTO, MASAHIKO;ODA, TOMIICHIRO
分类号 A61K31/16;A61K31/135;A61K31/165;A61K31/38;A61K31/381;A61K31/47;A61K31/535;A61K31/5375;A61P9/00;A61P25/28;A61P43/00;C07C57/03;C07C205/06;C07C233/07;C07C233/08;C07C235/32;C07C235/34;C07C235/36;C07C237/20;C07C237/22;C07D215/14;C07D215/38;C07D295/18;C07D295/185;C07D333/56;C07D333/68 主分类号 A61K31/16
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