发明名称 |
Platelet activating factor antagonists. |
摘要 |
<p>Indole compounds substituted at the 1- or 3-position by a (pyrid-3-yl)thiazolid-4-yl)alkyl-, (pyrid-3-yl)thiazolid-4-oyl)-, (pyrid-3-yl)dithiolan-4-yl)alkyl- or (pyrid-3-yl)dithiolan-4-oyl)- group are potent inhibitors of PAF and are useful in the treatment of PAF-related disorders including septic shock, respiratory distress syndrome, acute inflammation, delayed cellular immunity, parturtition, fetal lung maturation, and cellular differentiation.</p> |
申请公布号 |
EP0499987(A1) |
申请公布日期 |
1992.08.26 |
申请号 |
EP19920102532 |
申请日期 |
1992.02.14 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
SUMMERS, JAMES B.;SHEPPARD, GEORGE S.;PHILLIPS, JAMES G.;STEINMAN, DOUGLAS H.;GUINN, DENISE E.;CARRERA, GEORGE M, JR.;PIREH, DAISY;MAY, PAUL D.;HEYMAN, H. ROBIN;DAVIDSEN, STEVEN K. |
分类号 |
A61K31/44;A61K31/4427;A61K31/4433;A61P7/02;A61P11/00;A61P29/00;C07D401/14;C07D403/14;C07D409/14;C07D417/14 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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