| 摘要 |
The present invention relates to anti-tumor platinum complexes represented by the general formula I: <IMAGE> (I) wherein A is selected from the group consisting of ammine and mondentate primary alkyl- and cycloalkylamines having 1-3 carbon atoms such as methyl, ethyl, n-propyl-, isopropyl- and cyclopropylamines, or the two amine groups may be combined to be a bidentate diamine of the chelating form AA such as ethylenediamine, 1,2-diaminocyclohexane, and 2-hydroxy-1,3-diaminopropane, and X is either vinylene(-CH=CH-) or ethylene (-CH2-CH2-) when it is bound to two sulfur atoms in a cyclic form or represents two methyl groups separately bound to each sulfur atom.
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