PREPARATION OF ACYLATED SUCROSE DERIVATIVES

摘要

Sucrose derivatives partially acylated in each ring can be obtained by treating a fully or partially acylated sucrose derivative with an enzyme having sucrose esterase activity capable of removing at least one acyl group from each ring, generally comprising or being a component of a lipase, esterase, amylase, alpha -galactosidase or protease preparation, the enzyme treatment being effected in an aqueous system. Sucralose can be obtained by using this method to obtain a sucrose 2,3,6,3',4'-penta ester which can then be chlorinated and de-esterfied. Some of the penta acetates, tetraacetates and mixed acetates/butyrates are new compounds.