| 发明名称 |
ALPHA-ACYLAMINO AMINOALKYL PHOSPHONATE ANGIOTENSIN CONVERTING ENZYME INHIBITORS |
| 摘要 |
HA381 .alpha.-Acylamino Aminoalkyl Phosphonate Angiotensin Converting Enzyme Inhibitors Compounds of the formula wherein X is various amino or imino acids and esters are disclosed. These compounds are useful as anti-hypertensive agents due to their angiotensin converting enzyme inhibition activity and depending upon the definition of X may also be useful as analgesics due to their enkephalinase inhibition activity. |
| 申请公布号 |
CA1306749(C) |
申请公布日期 |
1992.08.25 |
| 申请号 |
CA19870539233 |
申请日期 |
1987.06.09 |
| 申请人 |
SQUIBB (E.R.) & SONS, INC. |
发明人 |
KARANEWSKY, DONALD S.;PETRILLO, EDWARD W., JR. |
| 分类号 |
C07F9/38;A61K31/66;A61P9/12;A61P25/04;C07F9/40;C07F9/547;C07F9/572;C07F9/58;C07F9/59;C07F9/62;C07F9/6503;C07F9/6506;C07F9/653;C07F9/6539;C07F9/6558;C07F9/6561 |
主分类号 |
C07F9/38 |
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