发明名称 |
INDOLES USEFUL AS PLATELET ACTIVATING FACTOR ANTAGONISTS |
摘要 |
2100682 9214732 PCTABS00015 Indole compounds substituted at the 1- or 3-position by a (pyrid-3-yl)thiazolid-4-yl)alkyl-, (pyrid-3-yl)thiazolid-4-oyl)-, (pyrid-3-yl)dithiolan-4-yl)alkyl- or (pyrid-3-yl)dithiolan-4-oyl)- group are potent inhibitors of PAF and are useful in the treatment of PAF-related disorders including septic shock, respiratory distress syndrome, acute inflammation, delayed cellular immunity, parturition, fetal lung maturation, and cellular differentiation.
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申请公布号 |
CA2100682(A1) |
申请公布日期 |
1992.08.21 |
申请号 |
CA19922100682 |
申请日期 |
1992.02.14 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
SUMMERS, JAMES B.;SHEPPARD, GEORGE S.;PHILLIPS, JAMES G.;PIREH, DAISY;STEINMAN, DOUGLAS H.;MAY, PAUL D.;GUINN, DENISE E.;HEYMAN, H. ROBIN;CARRERA, GEORGE M., JR.;DAVIDSEN, STEVEN K. |
分类号 |
A61K31/44;A61K31/4427;A61K31/4433;A61P7/02;A61P11/00;A61P29/00;C07D401/14;C07D403/14;C07D409/14;C07D417/14;(IPC1-7):C07D417/14;C07D413/14 |
主分类号 |
A61K31/44 |
代理机构 |
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