摘要 |
<p>The present invention relates to a surgical securing means having releaseably associated therewith a peptide, said peptide comprising the amino acid sequence: [aa]n-[RG-(x)n1]n2-[aa]n3 wherein R is arginine; G is glycine; x is aspartate or glutamate; aa is any amino acid; and n is 0-100; n1 is 0 or 1; n2 is 1 - 100; n3 is 0 - 100 and wherein said peptide is released in an amount effective to induce fibroblast-mediated collagen lattice contraction.</p> |