发明名称 Pyridine compounds as angiotensin II antagonists, processes for their preparation and pharmaceutical compositions containing them.
摘要 <p>The invention concerns pharmaceutically useful compounds of the formula I, in which R&lt;1&gt;, R&lt;2&gt;, R&lt;3&gt;, R&lt;4&gt;, R&lt;5&gt;, R&lt;6&gt;, R&lt;7&gt;, X and Z have the various meanings defined herein, and their non-toxic salts, and pharmaceutical compositions containing them. The novel compounds are of value in treating conditions such as hypertension and congestive heart failure. The invention further concerns processes for the manufacture of the novel compounds and the use of the compounds in medical treatment.</p>
申请公布号 EP0499416(A2) 申请公布日期 1992.08.19
申请号 EP19920301049 申请日期 1992.02.07
申请人 IMPERIAL CHEMICAL INDUSTRIES PLC 发明人 ROBERTS, DAVID ANTHONY;BRADBURY, ROBERT HUGH;EDWARDS, MARTIN PAUL;RATCLIFFE, ARNOLD HARY
分类号 A61K31/44;A61K31/4418;A61K31/4427;A61P9/00;A61P9/12;C07D213/60;C07D213/73;C07D213/78;C07D401/12;C07D401/14;C07D521/00 主分类号 A61K31/44
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