发明名称 |
Pyridine compounds as angiotensin II antagonists, processes for their preparation and pharmaceutical compositions containing them. |
摘要 |
<p>The invention concerns pharmaceutically useful compounds of the formula I, in which R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, X and Z have the various meanings defined herein, and their non-toxic salts, and pharmaceutical compositions containing them. The novel compounds are of value in treating conditions such as hypertension and congestive heart failure. The invention further concerns processes for the manufacture of the novel compounds and the use of the compounds in medical treatment.</p> |
申请公布号 |
EP0499416(A2) |
申请公布日期 |
1992.08.19 |
申请号 |
EP19920301049 |
申请日期 |
1992.02.07 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES PLC |
发明人 |
ROBERTS, DAVID ANTHONY;BRADBURY, ROBERT HUGH;EDWARDS, MARTIN PAUL;RATCLIFFE, ARNOLD HARY |
分类号 |
A61K31/44;A61K31/4418;A61K31/4427;A61P9/00;A61P9/12;C07D213/60;C07D213/73;C07D213/78;C07D401/12;C07D401/14;C07D521/00 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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