Therapy of conditions which may be associated with altered renal function and dosage forms therefor

摘要

The invention concerns a method of treating a subject suffering from abnormal distribution and retention of body fluids such as may be the result of altered renal function, which comprises the step of administering to a subject in need of such treatment, a therapeutically effective amount of a pharmaceutically acceptable alkaline acting substance capable of increasing patient plasma bicarbonate level to a value in excess of that prior to treatment. Oral preparations, in particular an alkaline substance capable of releasing bicarbonate ions, for therapy of a large variety of ailments and diseases, are disclosed.