| 发明名称 |
TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS WITH IMIDAZOLE ANGIOTENSIN-II RECEPTOR ANTAGONISTS |
| 摘要 |
Substituted imidazoles such as 2-butyl-4-chloro-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]-5-(hyd roxymethyl)imidazole and 2-butyl-4-chloro-1-[(2'-carboxybiphenyl-4-yl)-methyl]-5-(hydroxymethyl )imidazole and pharmaceutically acceptable salts thereof are useful for treating central nervous system disorders, such as cognitive and learning disorders, mediated by angiotensin II.
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| 申请公布号 |
US5140037(A) |
申请公布日期 |
1992.08.18 |
| 申请号 |
US19900497063 |
申请日期 |
1990.03.20 |
| 申请人 |
E. I. DU PONT DE NEMOURS AND COMPANY |
发明人 |
CHIU, ANDREW T.;DENOBLE, VICTOR J.;DUNCIA, JOHN J. V.;WONG, PANCRAS C. B. |
| 分类号 |
A61K31/41;A61K31/415;A61K31/4174;A61K31/4178;A61K31/495;A61K31/675;A61P25/28;A61P43/00;C07D233/56;C07D233/60;C07D233/61;C07D403/10 |
主分类号 |
A61K31/41 |
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