New nitrogenous bicyclic derivatives substituted with a benzyl radical, process for their preparation, the new intermediates obtained and their application as medicaments

摘要

The subject of the invention is the products of formula (I): <IMAGE> in which: R2 and R3 represent: hydrogen, halogen, hydroxyl, mercapto, cyano, nitro, sulpho, formyl, benzoyl, acyl, carboxyl, in the free, salified or esterified form, cycloalkyl, alkyl, alkenyl, alkynyl, alkyloxy, alkylthio, aryl, arylalkyl, arylalkenyl, aryloxy, arylthio, <IMAGE> or <IMAGE> , A1, A2, A3 and A4 are such that: - one represents a nitrogen atom, - another represents a nitrogen atom or the <IMAGE> radical, - another represents the <IMAGE> radical, - and the last represents the methine radical substituted with the benzyl radical, the said products of formula (I) being in all the possible racemic, enantiomeric and diastereoisomeric isomeric forms, and the addition salts of the said products of formula (I). These products have advantageous pharmacological properties which justify their use as medicaments.