STEREOSPEZIFISCHE KETOREDUKTION VON BICYCLOOCTANDION-CARBONSAEUREESTERN DURCH MIKROORGANISMEN.

摘要

Prodn. of 3alpha-hydroxy-bicyclooctane cpds. of formula (I) comrpises treating the racemic oxo cpd. (II) with a Rhizopus, Thodotorula or Candida strain. Where the strain used reduces the (-) form, the unchanged (+)-(II) is reduced subsequently by a chemical or microbiological process. A = CH2 or CH-COOR; B = O or -O-X-O-; X = opt. branched 1-7C alkylene; R = 1-6C alkyl or benzyl.