发明名称 Bicyclic nitrogen compounds, their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them.
摘要 <p>The subject of the invention is the products of formula (IB): <IMAGE> in which: R2B and R3B, which are identical or different, represent hydrogen; halogen; hydroxyl; mercapto; cyano; nitro; sulpho; formyl; benzoyl; acyl; carboxy in the free, salt or ester form; cycloalkyl; acyloxy; alkyl; alkenyl; alkynyl; alkyloxy; alkylthio; aryl; arylalkyl; arylalkenyl; aryloxy or arylthio; d) a radical <IMAGE> where R6B, R7B, R8B and R9B represent hydrogen or optionally substituted alkyl, alkenyl, aryl or arylalkyl, or -(CH2)m1-S(O)m2-X-R14, where m1 represents 0 to 4, m2 represents 0 to 2, X-R14 represents -NH2 or X represents -NH , NH-CO-, -NH-CO-NH- or a single bond and R14 represents optionally substituted alkyl, alkenyl or aryl.</p>
申请公布号 EP0498722(A1) 申请公布日期 1992.08.12
申请号 EP19920400295 申请日期 1992.02.05
申请人 ROUSSEL-UCLAF 发明人 CLEMENCE, FRANCOIS;FORTIN, MICHEL;HAESSLEIN, JEAN-LUC
分类号 A61K31/47;A61K31/472;A61K31/495;A61K31/50;A61K31/502;A61K31/505;A61K31/517;A61P1/00;A61P9/00;A61P9/08;A61P9/10;A61P9/12;A61P11/06;A61P13/02;A61P15/00;A61P25/28;A61P27/06;C07C229/30;C07D215/12;C07D215/14;C07D215/20;C07D215/22;C07D215/233;C07D215/48;C07D217/12;C07D217/18;C07D217/22;C07D217/24;C07D217/26;C07D237/28;C07D237/30;C07D239/72;C07D241/40 主分类号 A61K31/47
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