发明名称 |
PIPERAZINE SUBSTITUTED PYRIMIDINE DERIVATIVES AND PHYSIOLOGICALLY TOLERATED SALTS THEREOF |
摘要 |
Pyrimidine derivatives of the formula I <IMAGE> I in which R1, R2, R3, R4 and R5 have the indicated meanings, the salts thereof, and a process for the preparation thereof are described. Because of their sorbitol-accumulating activity, they are suitable as a tool in a pharmacological screening model for aldose reductase inhibitors.
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申请公布号 |
US5138058(A) |
申请公布日期 |
1992.08.11 |
申请号 |
US19900482053 |
申请日期 |
1990.02.20 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
GEISEN, KARL;LANG, HANS-JOCHEN;NIMMESGERN, HILDEGARD;WEIDMANN, KLAUS |
分类号 |
A61K31/505;A61K49/00;A61P3/08;A61P3/10;C07D239/42;C07D239/47;C07D239/48;C07D401/12 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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