发明名称 |
OLIGOPEPTIDE ANTIRETROVIRAL AGENTS |
摘要 |
Oligopeptide antiretroviral agents are represented by the formula: wherein A is a moiety bearing a positive charge and of a size which avoids steric inhibition of binding of said compound to nucleic acid sequences associated with the cellular activity of retroviruses; R1 is a moiety derived from a dicarboxylic acid; Het is a five-membered heterocyclic moiety; y and z are independently 0, 1, 2 or 3; and x is 0 or 1. These compounds exhibit antiretroviral activity, especially against Human Immunodeficiency Virus (HIV).
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申请公布号 |
CA2103665(A1) |
申请公布日期 |
1992.08.07 |
申请号 |
CA19922103665 |
申请日期 |
1992.02.05 |
申请人 |
SYNPHAR LABORATORIES, INC. |
发明人 |
LOWN, J. WILLIAM;MICETICH, RONALD G. |
分类号 |
C07D207/34;C07D233/90;C07D401/14;(IPC1-7):C07K5/027;C07D249/02;A61K38/06;A61K31/33;C07D333/38;C07D231/40;C07D263/48;C07D277/56;C07D307/68 |
主分类号 |
C07D207/34 |
代理机构 |
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代理人 |
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地址 |
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