SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS

摘要

This invention relates to compounds having selective LTB4 antagonist properties. Therapeutic compositions comprising said compounds and methods for the treatment of disorders involving LTB4 agonist-mediated activity utilizing said compositions wherein the compounds are described by the formula wherein R4, X, R, Y, R', Q, m and n are herein defined, and pharmaceutically acceptable salts thereof.