| 发明名称 |
MONOCLONAL ANTIBODIES TO ELAM-1 AND THEIR USES |
| 摘要 |
Compositions and methods are provided for inhibiting inflammatory and other disease responses mediated by ELAM-1. In particular, the present invention provides immunoglobulins which selectively bind functional epitopes on ELAM-1 and block adhesion of leukocytes to activated endothelial cells both in vitro and in vivo. |
| 申请公布号 |
WO9212729(A1) |
申请公布日期 |
1992.08.06 |
| 申请号 |
WO1992US00577 |
申请日期 |
1992.01.23 |
| 申请人 |
CYTEL CORPORATION |
发明人 |
WAYNER, ELISABETH;PHILLIPS, MARY, L.;WINKELHAKE, JEFFREY, L. |
| 分类号 |
A61K9/127;A61K38/00;A61K39/00;A61K39/395;A61K47/48;A61P29/00;C07K16/28;C12N5/12;C12P21/08 |
主分类号 |
A61K9/127 |
| 代理机构 |
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