发明名称 Method for renaturing proteins in the presence of alkyl sulfate detergents
摘要 A high concentration of renaturing surfactants is added to protein systems in the presence of alkyl sulfate detergents to displace the detergent with respect to the interaction with the protein, thereby renaturing the protein and restoring its reactivity. The presence of higher quantities of detergent in the system results in smaller protein aggregates, and thus a higher reactivity and specificity as measured for the system in its entirety.
申请公布号 US5136027(A) 申请公布日期 1992.08.04
申请号 US19890346508 申请日期 1989.05.02
申请人 ABBOTT LABORATORIES 发明人 POPE, MARK R.
分类号 C07K1/113;C07K14/16 主分类号 C07K1/113
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