| 摘要 |
PCT No. PCT/GB89/00813 Sec. 371 Date Mar. 22, 1991 Sec. 102(e) Date Mar. 22, 1991 PCT Filed Jul. 14, 1989 PCT Pub. No. WO90/01029 PCT Pub. Date Feb. 8, 1990.A method of preparing a nitrate ester of an epoxy alcohol, which consists of reacting an epoxy alcohol with N2O5 in an inert solvent at a temperature of -10 DEG C. to -40 DEG C., followed by quenching the reaction mixture in aqueous solution. Quenching separates the nitric acid and nitrate ester coproducts into aqueous and organic phases respectively to prevent subsequent reaction between the two. Reaction between the nitric acid coproduct and epoxy alcohol reagent to produce acyclic contaminants is supressed by adding the epoxy alcohol to excess N2O5, thereby rapidly converting available alcohol to nitrate ester.
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