| 发明名称 |
Squalene synthetase inhibitors |
| 摘要 |
Compounds of structural formula (I): <IMAGE> (I) are squalene synthestase inhibitors useful in inhibiting the biosynthesis of cholesterol in the treatment of hypercholesterolemia and related disorders.
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| 申请公布号 |
US5135935(A) |
申请公布日期 |
1992.08.04 |
| 申请号 |
US19910701922 |
申请日期 |
1991.05.17 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
ALBERTS, ALFRED W.;BERGER, GREGORY D.;BERGSTROM, JAMES D. |
| 分类号 |
A61K31/44;A61K31/455;A61K31/47;C07D453/02 |
主分类号 |
A61K31/44 |
| 代理机构 |
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| 地址 |
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