发明名称 NEW COMPOUND, VASODILATOR AND SKIN MEDICINE FOR EXTERNAL USE CONTAINING THE SAME
摘要 PURPOSE:To obtain a compound such as erectumins A and B useful as a vasodilator, a skin medicine for external use, etc. CONSTITUTION:A compound expressed by formula I (R1 is H or Group expressed by formula II; R2 is H or CH3; the asterisk mark indicates asymmetric carbon atom), e.g. erectumins A and B in which R1 is the group expressed by formula II and R2 is H. The aforementioned compound is obtained by initially pulverizing Hypericum erectum Thunb., adding a solvent such as methanol or acetone to the pulverized substance, carrying out dipping and extracting at 10-60 deg.C for 1 day to 1 week, subjecting the resultant essence of the extract solution to liquid-liquid partition with methanol, water and n-hexane and fractionating the prepared n-hexane fraction.
申请公布号 JPH04211676(A) 申请公布日期 1992.08.03
申请号 JP19910036890 申请日期 1991.02.06
申请人 KAO CORP 发明人 JOKURA YOJI;KAMIYA TETSURO;NISHIZAWA YOSHINORI
分类号 A61K31/365;A61K36/18;A61P9/08;A61P9/12;A61P17/00;C07D307/60 主分类号 A61K31/365
代理机构 代理人
主权项
地址