| 摘要 |
PURPOSE:To produce the subject compound useful as raw materials for medicines and agricultural chemicals by an extremely simple post-treatment operation in a high yield by chlorinating toluene or monochlorotoluene in liquid phase in the presence of activated alumina as a catalyst. CONSTITUTION:Toluene(TOL) or monochlorotoluene(MCT) is chlorinated in liquid phase in the presence of activated alumina to produce the subject compound. The activated alumina is a quasi-stable alumina excluding alpha-alumina, generally exemplified by gamma-,delta-,eta-,theta-,kappa-,rho or chi-alumina. The feed ratio of chlorine to the reaction system is 0.01 to 0.1mol/g-cat.hr. The feed amount of TOL or MCT is preferably 0.05-1mol per 1.0g of the activated alumina for batchwise system, and 0.01-0.1mol/g-cat.hr for continuous system. In the process the production of highly nucleus-substituted chlorinated product is minimized, and the post-treatment is simplified. |
