EFFICIENT RIBOFLAVIN PRODUCTION WITH YEAST

摘要

16 EFFICIENT RIBOFLAVIN PRODUCTION WITH YEAST A method of systematically generating and isolating highly flavinogenic strains of Candida flareri. The strains Candida flareri GA18Y8-6#2 dgr and Candida flareri GA18Y8-6#2#11 have been developed and produce yields of ca. 7.0 to 7.5 grams per liter per 6 days. The method includes a combination of iterative mutagenizing steps and protoplast fusion steps performed on the parent strain and the descendant strains which are selected following each step according to a screening protocol. AAAAA1/00950-2