CEPHALOSPORIN ANTIBIOTICS

摘要

PCT No. PCT/US88/03435 Sec. 371 Date May 9, 1990 Sec. 102(e) Date May 9, 1990 PCT Filed Oct. 11, 1988 PCT Pub. No. WO89/04313 PCT Pub. Date May 18, 1989.Cephalosporin compounds of Formulas II <IMAGE> Formula II where R is hydrogen or a pharmaceutical cation, in which case R1 is not present, or R is hydrogen or a chemical bond when R1 is an acid addition salt anion, and R2 is (a) hydrogen, (b) a duplicate of the formula I compound to form a dimer, (c) an aminocarbonylmethyl, or (d) an -SR3 group where R3 is alkyl, cyclohexyl, phenyl, chloro-substituted phenyl, nitro-substituted phenyl, benzyl or furfuryl, have been found to be valuable as antibiotics for treating warm-blooded animals to combat pathogenic bacterial infections which cause diseases such as the commonly known "shipping fever".