发明名称 Antihypertensive 3-piperidinyl-indazole derivatives
摘要 Novel antihypertensive 3-piperidinyl-indazole derivatives of formula <CHEM> wherein R<1> is hydrogen or C1-6alkyl; R<2> is hydrogen; C1-6alkyl; substituted C1-6alkyl; optionally substituted phenyl; C1-6alkylcarbonyl; C1-6alkyloxycarbonyl or phenylcarbonyl, wherein phenyl may be substituted; R<3> and R<4> are hydrogen, halo, hydroxy, C1-6alkyloxy or C1-6alkyl; Q is a bicyclic heterocyclic radical of formula <CHEM> the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, which compounds are antihypertensive agents; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
申请公布号 PH26456(A) 申请公布日期 1992.07.27
申请号 PH19280000391 申请日期 1989.08.22
申请人 JANSSEN PHARMACEUTICA N.V. 发明人 JAN VANDENBERK;LUDO E. J. KENNIS;ALBERTUS H. M. T. VAN HEERTUM
分类号 A61K31/4184;A61K31/44;A61K31/4427;A61K31/445;A61K31/505;A61P1/12;A61P3/04;A61P9/12;A61P25/00;A61P25/06;A61P25/18;A61P25/24;A61P25/30;A61P25/32;A61P25/34;A61P43/00;C07D401/14;C07D471/04;C07D498/04;C07D513/04;C07D521/00 主分类号 A61K31/4184
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