发明名称 |
Antihypertensive 3-piperidinyl-indazole derivatives |
摘要 |
Novel antihypertensive 3-piperidinyl-indazole derivatives of formula <CHEM> wherein R<1> is hydrogen or C1-6alkyl; R<2> is hydrogen; C1-6alkyl; substituted C1-6alkyl; optionally substituted phenyl; C1-6alkylcarbonyl; C1-6alkyloxycarbonyl or phenylcarbonyl, wherein phenyl may be substituted; R<3> and R<4> are hydrogen, halo, hydroxy, C1-6alkyloxy or C1-6alkyl; Q is a bicyclic heterocyclic radical of formula <CHEM> the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, which compounds are antihypertensive agents; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions. |
申请公布号 |
PH26456(A) |
申请公布日期 |
1992.07.27 |
申请号 |
PH19280000391 |
申请日期 |
1989.08.22 |
申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
JAN VANDENBERK;LUDO E. J. KENNIS;ALBERTUS H. M. T. VAN HEERTUM |
分类号 |
A61K31/4184;A61K31/44;A61K31/4427;A61K31/445;A61K31/505;A61P1/12;A61P3/04;A61P9/12;A61P25/00;A61P25/06;A61P25/18;A61P25/24;A61P25/30;A61P25/32;A61P25/34;A61P43/00;C07D401/14;C07D471/04;C07D498/04;C07D513/04;C07D521/00 |
主分类号 |
A61K31/4184 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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